Dr. Mary Ellen Guffey: Either quotation marks or italics serve the same purpose in calling attention to words used in a special sense.
Ruth E. Thaler-Carter: If it's in quotes, it needn't be bold as well. Same for italic.
Tara McDonough: In many cases, italics are not viable (e-mail, web forms), though in a Word document, it might be a different story.
Rob Ault: I prefer italics if they're available, but if not than I'll use quotation marks.
Yvonne Klein: any will do
Jennifer German: This really depends upon context. If someone else has said/written to me to provide info using correct usage, I'd choose A or B. If I were writing test, I'd say C.
Yocheved Golani: Suits the grammatical standard.
Elizabeth Platt: I'd take either 1 or 2 but not 3.
Beverly Foster: I use it without the bold.
Jodi Lipson: no bold
Mark H. Bloom: This is normally a style guide issue. The first choice is overkill. Either of the other choices is acceptable, as long as the style is used consistently.